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HDAC6 Antibody

CAT: 0800-F54055-0.1MLSize: 0.1 mLDry Ice: NoHazardous: No
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CAT#:0800-F54055-0.1MLSize:0.1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) . Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity) . Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. [UniProt]
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
Q9UBN7
Host
Mouse
Reactivity
Human
Immunogen
A human recombinant protein was used as the immunogen for this HDAC6 antibody.
Clonality
Monoclonal
Isotype
LgG2a
Clone
3B2-F5-G6
Applications
WB
Purity
Protein G affinity
Format
Purified
Buffer
Antibody in PBS with 50% Glycerol and 0.03% ProClin 300
Reconstitution
Store the HDAC6 antibody at -20oC.
Limitations
This HDAC6 antibody is available for research use only.
Storage Conditions
Store the HDAC6 antibody at -20°C.
Formulation
In PBS with 50% glycerol and 0.03% ProClin 300
Applications Notes
The stated application concentrations are suggested starting points. Titration of the HDAC6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of lysates from human T47D, Jurkat, untransfected CHO-K1 (B) and CHO-K1 transfected with an HDAC6 fragment (A) using HDAC6 antibody at 1:1000. Predicted molecular weight: 130-160 kDa (full length), ~55 kDa (partial) .
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