Products for Research Use Only

SIRT2 Antibody

CAT: 0800-F54053-0.1MLSize: 0.1 mLDry Ice: NoHazardous: No
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CAT#:0800-F54053-0.1MLSize:0.1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sirtuin 2 is an NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and alpha-tubulin as well as many other proteins such as key transcription factors. Participates in the modulation of multiple and diverse biological processes such as cell cycle control, genomic integrity, microtubule dynamics, cell differentiation, metabolic networks, and autophagy. Plays a major role in the control of cell cycle progression and genomic stability. [UniProt]
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, ICC/IF: 1:50
UniProt
Q8IXJ6
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
A human recombinant protein was used as the immunogen for this SIRT2 antibody.
Clonality
Monoclonal
Isotype
IgG2b
Clone
1D4-H11-H11
Applications
WB, ICC/IF
Purity
Protein G affinity
Format
Purified
Buffer
Antibody in PBS with 50% Glycerol and 0.03% ProClin 300
Reconstitution
Store the SIRT2 antibody at -20oC.
Limitations
This SIRT2 antibody is available for research use only.
Storage Conditions
Store the SIRT2 antibody at -20°C.
Formulation
Antibody in PBS with 50% glycerol and 0.03% ProClin 300
Applications Notes
The stated application concentrations are suggested starting points. Titration of the SIRT2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
ICC/IF analysis of HeLa cells, fixed fixed by anhydrous methanol at -20°C, using SIRT2 antibody at 1:50 (green) and Histone H3.1 (pSer10) antibody at 1:200 (red) .

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