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AKT2 Antibody / PKB beta

CAT: 0800-F53805-0.05MLSize: 0.05 mLDry Ice: NoHazardous: No
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CAT#:0800-F53805-0.05MLSize:0.05 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AKT2 is one of three closely related serine/threonine- protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000-1:2000
UniProt
P31751
Host
Mouse
Reactivity
Human, Rat
Immunogen
Human recombinant protein corresponding to amino acids 272-481 was used as the immunogen for this AKT2 antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
1623CT791.157.67.66
Applications
WB
Purity
Protein G affinity chromatography
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the AKT2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This AKT2 antibody is available for research use only.
Storage Conditions
Aliquot the AKT2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the AKT2 antibody may be required due to differences in protocols and substrate sensitivity.
Image Legend
Western blot testing of 1) human MCF7, 2) human Jurkat and 3) rat PC-12 cell lysate with AKT2 antibody at 1:2000. Predicted molecular weight: 56 kDa.

UniProtKB · P31751

RAC-beta serine/threonine-protein kinase

AKT2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P31751
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
AKT2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.1
Processing
—
Secondary accessions
B2RBD8, Q05BV0, Q0VAN0, Q0VAN1, Q68GC0
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationDisulfide bondGlycoproteinPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisCarbohydrate metabolismGlucose metabolismGlycogen biosynthesisGlycogen metabolismSugar transportTranslation regulationTransport

Ligand

ATP-bindingManganeseMetal-bindingNucleotide-binding

Cellular component

Cell membraneCytoplasmEndosomeMembraneNucleus

Molecular function

Developmental proteinKinaseSerine/threonine-protein kinaseTransferase

Disease

Diabetes mellitusDisease variantProto-oncogene
Product Datasheet
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