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AKT2 Antibody

CAT: 0800-F40226-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
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CAT#:0800-F40226-0.4MLSize:0.4 mL
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Description
AKT2 is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.
CAS Number
9007-83-4
UniProt
P31751
Host
Mouse
Immunogen
This anti-AKT2 antibody was produced from a mouse immunized with AKT2 recombinant protein.
Clonality
Monoclonal
Isotype
IgG1
Applications
WB, IHC, IF, ELISA
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the anti-AKT2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This anti-AKT2 antibody is available for research use only.

UniProtKB · P31751

RAC-beta serine/threonine-protein kinase

AKT2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P31751
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
AKT2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.1
Processing
—
Secondary accessions
B2RBD8, Q05BV0, Q0VAN0, Q0VAN1, Q68GC0
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationDisulfide bondGlycoproteinPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisCarbohydrate metabolismGlucose metabolismGlycogen biosynthesisGlycogen metabolismSugar transportTranslation regulationTransport

Ligand

ATP-bindingManganeseMetal-bindingNucleotide-binding

Cellular component

Cell membraneCytoplasmEndosomeMembraneNucleus

Molecular function

Developmental proteinKinaseSerine/threonine-protein kinaseTransferase

Disease

Diabetes mellitusDisease variantProto-oncogene
Product Datasheet
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