IGF2 Antibody

• Description:

  This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• Specifications:

  Western blot: 1:500-1:8000

• UniProt:

  P01344

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  A portion of amino acids 39-68 from the human protein was used as the immunogen for this IGF2 antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgM

• Clone:

  519CT14.3.6

• Applications:

  WB, ELISA

• Purity:

  Ascites

• Format:

  Ascites

• Buffer:

  In ascites with 0.09% sodium azide

• Reconstitution:

  Aliquot the IGF2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This IGF2 antibody is available for research use only.

• Storage Conditions:

  Aliquot the IGF2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In ascites with 0.09% sodium azide

• Applications Notes:

  Titration of the IGF2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4

• Image Legend:

  IGF2 antibody western blot analysis in A549 lysate. Predicted molecular weight: 20, 20, 26 kDa (isoforms 1-3) .