Cdc25A Antibody

• Description:

  CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.

• Specifications:

  Western blot: 1:1000

• UniProt:

  P30304

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This Cdc25A antibody was produced from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human Cdc25A.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  WB, ELISA

• Purity:

  Antigen affinity

• Format:

  Antigen affinity purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the Cdc25A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This Cdc25A antibody is available for research use only.

• Storage Conditions:

  Aliquot the Cdc25A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  Titration of the Cdc25A antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4

• Image Legend:

  Western blot analysis of Cdc25A antibody and mouse kidney tissue lysate. Predicted molecular weight: 59-70 kDa.