CDC25C Antibody

• Description:

  This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. [provided by RefSeq].

• Specifications:

  Western blot: 1:1000-1:8000

• UniProt:

  P30307

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  This CDC25C antibody was produced from mouse immunized with CDC25C recombinant protein.

• Clonality:

  Monoclonal

• Isotype:

  IgG1 k

• Clone:

  233CT9.6.6

• Applications:

  WB, ELISA

• Purity:

  Ascites

• Format:

  Ascites

• Limitations:

  This CDC25C antibody is available for research use only.

• Storage Conditions:

  Aliquot the CDC25C antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In ascites with 0.09% sodium azide

• Applications Notes:

  Titration of the CDC25C antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• Image Legend:

  Western blot analysis of CDC25C antibody and 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (2) with the CDC25C gene. Expected molecular weight: ~53/60 kDa (unmodified/phosphorylated) .