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Phospho-Cdc25A Antibody (pS79)

CAT: 0800-F48558-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
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CAT#:0800-F48558-0.08MLSize:0.08 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CDC25A is a member of the CDC25 family of phosphatases.CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division.CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.
CAS Number
9007-83-4
Specifications
Dot blot: 1:500
UniProt
P30304
Host
Rabbit
Reactivity
Human
Immunogen
This phospho-Cdc25A antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS79 of human Cdc25A.
Clonality
Polyclonal
Isotype
Ig
Applications
DB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the phospho-Cdc25A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This phospho-Cdc25A antibody is available for research use only.
Storage Conditions
Aliquot the phospho-Cdc25A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the phospho-Cdc25A antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Bovine, Mouse, Rat
Image Legend
Dot blot analysis of phospho-Cdc25A antibody. 50ng of phos-peptide or nonphos-peptide per dot were spotted.

UniProtKB · P30304

M-phase inducer phosphatase 1

MPIP1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P30304
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CDC25A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.1.3.48
Processing
—
Secondary accessions
Q8IZH5, Q96IL3, Q9H2F2
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Cell cycleCell divisionMitosis

Molecular function

HydrolaseProtein phosphatase

PTM

PhosphoproteinUbl conjugation

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