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SIRT4 Antibody

CAT: 0800-F46292-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
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CAT#:0800-F46292-0.4MLSize:0.4 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
Q9Y6E7
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 67-95 from the human protein was used as the immunogen for this SIRT4 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the SIRT4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This SIRT4 antibody is available for research use only.
Storage Conditions
Aliquot the SIRT4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the SIRT4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Bovine
Image Legend
SIRT4 antibody western blot analysis in mouse testis tissue lysate.

UniProtKB · Q9Y6E7

NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

SIR4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y6E7
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SIRT4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.3.1.313
Processing
Precursor
Secondary accessions
O43346, Q32M33
Protein keywords

Technical term

Direct protein sequencingProteomics identificationReference proteome

Biological process

DNA damage

Molecular function

GlycosyltransferaseNucleotidyltransferaseTransferase

Ligand

Metal-bindingNADZinc

Cellular component

Mitochondrion

Domain

Transit peptide

Disease

Tumor suppressor

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