Cdk9 Antibody

• Description:

  Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to production elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II), SUPT5H and RDBP. The CDK9/cyclin-K complex has also a kinase activity toward CTD of RNAP II and can substitute for P-TEFb in vitro (By similarity) .

• Specifications:

  Western blot: 1:1000

• UniProt:

  Q99J95

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A portion of amino acids 251-278 from the mouse protein was used as the immunogen for this Cdk9 antibody.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  WB, ELISA

• Purity:

  Antigen affinity

• Format:

  Antigen affinity purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the Cdk9 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This Cdk9 antibody is available for research use only.

• Storage Conditions:

  Aliquot the Cdk9 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  Titration of the Cdk9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• Prediction Reactivity:

  Bovine

• CAS Number:

  9007-83-4

• Image Legend:

  Western blot analysis of lysate from 1) human 293, 2) mouse NIH3T3, 3) rat C6 cell line and 4) mouse kidney tissue lysate using Cdk9 antibody at 1:1000. Predicted molecular weight ~43 kDa.