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Caspase-2 Antibody

CAT: 0800-F42862-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
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CAT#:0800-F42862-0.08MLSize:0.08 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CASP2 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. The protein exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of this protein is induced by a variety of apoptotic stimuli.
CAS Number
9007-83-4
UniProt
P42575
Host
Rabbit
Immunogen
A portion of amino acids 198-226 from the human protein was used as the immunogen for this Caspase-2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, FACS, ELISA
Format
Purified
Buffer
In 1X PBS pH 7.4 with 0.09% sodium azide
Reconstitution
Aliquot the Caspase-2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Caspase-2 antibody is available for research use only.

UniProtKB · P42575

Caspase-2

CASP2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P42575
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CASP2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
CASP-2
EC number
3.4.22.55
Processing
Precursor
Secondary accessions
A8K5F9, D3DXD6, E9PDN0, P42576, Q59F21, Q7KZL6, Q86UJ3, Q9BUP7, Q9BZK9, Q9BZL0
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoproteinZymogen

Coding sequence diversity

Alternative splicing

Biological process

Apoptosis

Disease

Disease variantIntellectual disabilityLissencephaly

Molecular function

HydrolaseProteaseThiol protease
Product Datasheet
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