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Caspase-6 Antibody

CAT: 0800-F42752-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
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CAT#:0800-F42752-0.08MLSize:0.08 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CASP6 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This protein could be processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade.
CAS Number
9007-83-4
UniProt
P55212
Host
Rabbit
Immunogen
A portion of amino acids 235-263 from the human protein was used as the immunogen for this Caspase-6 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, ELISA
Format
Antigen affinity purified
Buffer
In 1X PBS pH 7.4 with 0.09% sodium azide
Reconstitution
Aliquot the Caspase-6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Caspase-6 antibody is available for research use only.

UniProtKB · P55212

Caspase-6

CASP6_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P55212
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CASP6
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
CASP-6, CSP-6
EC number
3.4.22.59
Processing
Precursor
Secondary accessions
Q9BQE7
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Apoptosis

PTM

Autocatalytic cleavageLipoproteinPalmitatePhosphoproteinZymogen

Cellular component

CytoplasmNucleus

Molecular function

HydrolaseProteaseThiol protease
Product Datasheet
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