Caspase-10 Antibody

CAT: 0800-F42859-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No

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CAT#:0800-F42859-0.08MLSize:0.08 mL

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Description

CASP10 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in the protein are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome.

CAS Number

9007-83-4

UniProt

Q92851

Host

Rabbit

Immunogen

A portion of amino acids 164-192 from the human protein was used as the immunogen for this Caspase-10 antibody.

Clonality

Polyclonal

Isotype

Applications

WB, ELISA

Format

Purified

Buffer

In 1X PBS pH 7.4 with 0.09% sodium azide

Reconstitution

Aliquot the Caspase-10 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Caspase-10 antibody is available for research use only.

UniProtKB · Q92851

Caspase-10

CASPA_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q92851
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: CASP10
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: CASP-10
EC number: 3.4.22.63
Processing: Precursor
Secondary accessions: Q68HC0, Q6KF62, Q6KF63, Q8IUP5, Q8WYQ8, Q99845, Q9Y2U6, Q9Y2U7

Protein keywords

Coding sequence diversity

Alternative splicing

Biological process

Apoptosis

Technical term

Direct protein sequencingProteomics identificationReference proteome

Disease

Disease variant

Molecular function

HydrolaseProteaseThiol protease

Domain

Repeat

PTM

Zymogen

Product Datasheet

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Alternative Products

Catalog	Name
70R-49477	Caspase 10 antibody
6677-30T	Caspase-10 Antibody
GWB-F8DFB6	Caspase 10, Antibody