PEG2000-C-DMG

CAT: 0804-HY-145411-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0804-HY-145411-01Size:25 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
PEG2000-C-DMG, a pegylated lipid, can be used for the preparation of Onpattro. Onpattro, a hepatically directed investigational RNAi therapeutic agent, harnesses this process to reduce the production of mutant and wild-type transthyretin by targeting the 3′ untranslated region of transthyretin mRNA[1][2].
CAS Number
[1443687-74-8]
UNSPSC
12352211
Target
Liposome
Type
Oligonucleotides
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/peg2000-c-dmg.html
Purity
99.97
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCCCCCCCCCCCCC(O[C@@H](COC(NCCCOCCOC)=O)COC(CCCCCCCCCCCCC)=O)=O.[45]
Molecular Formula
C126H249NO52
Molecular Weight
2610.29
References & Citations
[1]Garber K. Alnylam launches era of RNAi drugs. Nat Biotechnol. 2018;36 (9) :777-778. |[2]Adams D, Gonzalez-Duarte A, O'Riordan WD, et al. Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis. N Engl J Med. 2018;379 (1) :11-21.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported

Related Products

CatalogName
HY-W1049124APEG5000-C-DMG
HY-168399-01PEG (2000) -C-DMG
HY-W440931MPEG2000-DMG
HY-N16040-01DMG-pSar25
HY-141674DMG-PEG
HY-Y0873B-01PEG2000
HY-112764ADMG-PEG (Excipient)
HY-W800830DMG-Nitrophenyl carbonate
HY-N15976DMG-pSar25 Maleimide
HY-112764-01DMG-PEG 2000

Alternative Products

CatalogName
MF-0154724PEG2000-C-DMG
14493-100DMG-PEG2000
M2004-250DMG-PEG2000-NHS
M2007-10DMG-PEG2000-Biotin
M2012-10DMG-PEG2000-N3
B2013390DMG PEG2000 Alkyle
B2013630Cy3 DMG PEG2000
M2005-100DMG-PEG2000-MAL
M2006-250DMG-PEG2000-NH₂
B2013236DMG PEG2000 DBCO Conjugate

Popular Products