PEG5000-C-DMG

• Description:

  PEG5000-C-DMG is a PEGylated derivative of 1,2-Dimyristoyl-sn-glycerol (HY-128468) . PEG5000-C-DMG can be combined with other lipids to form lipid nanoparticles (LNPs) for the delivery of siRNA[1].

• UNSPSC:

  12352200

• Target:

  Liposome

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Cancer

• Smiles:

  CCCCCCCCCCCCCC(OC(COC(NCCCOCCOC)=O)COC(CCCCCCCCCCCCC)=O)=O.[n]

• Molecular Formula:

  (C2H4O) nC36H69NO7

• Molecular Weight:

  5000 (average)

• References & Citations:

  [1]Hobo W, et al. Improving dendritic cell vaccine immunogenicity by silencing PD-1 ligands using siRNA-lipid nanoparticles combined with antigen mRNA electroporation. Cancer Immunol Immunother. 2013 Feb;62 (2) :285-97.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Biochemical Assay Reagents

• Clinical Information:

  No Development Reported

• CAS Number:

  1443687-74-8