DMG-PEG 2000

• Description:

  DMG-PEG 2000 is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG 2000 is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles[1].

• UNSPSC:

  12352211

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Liposome

• Type:

  Oligonucleotides

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/dmg-peg-2000.html

• Purity:

  98.40

• Solubility:

  DMSO : 125 mg/mL (ultrasonic; warming; heat to 60°C) |Ethanol : 100 mg/mL (ultrasonic) |H2O : 16.67 mg/mL (ultrasonic)

• Smiles:

  CCCCCCCCCCCCCC(OC(COCCOC)COC(CCCCCCCCCCCCC)=O)=O.[n]

• Molecular Formula:

  (C2H4O) nC32H62O5

• Molecular Weight:

  2000 (Average)

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Tianqi Nie, et al. Surface Coating Approach to Overcome Mucosal Entrapment of DNA Nanoparticles for Oral Gene Delivery of Glucagon-like Peptide 1.ACS Appl Mater Interfaces. 2019 Aug 21;11 (33) :29593-29603.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture and light)

• Scientific Category:

  Oligonucleotides

• Clinical Information:

  No Development Reported

• CAS Number:

  [160743-62-4]