NaV1.2/1.6 channel blocker-1
CAT:
804-HY-152166-03
Size:
25 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
NaV1.2/1.6 channel blocker-1
- CAS Number: 1199944-04-1
- UNSPSC Description: NaV1.2/1.6 channel blocker-1 is a potent NaV1.2/1.6 channel blocker, with IC50s of 9.8 and 24.4 μM for rNaV1.6 and hNaV1.2, respectively. NaV1.2/1.6 channel blocker-1 can be used for the research of generalized epilepsy[1].
- Target Antigen: Sodium Channel
- Type: Reference compound
- Related Pathways: Membrane Transporter/Ion Channel
- Applications: Neuroscience-Neuromodulation
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/nav1-2-1-6-channel-blocker-1.html
- Solubility: DMSO : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: S=C1OC2=CC=CC=C2C3=NC(C)=C(CCC)N13
- Molecular Weight: 258.34
- References & Citations: [1]Rivara M, et, al. Biological Evaluation of Imidazobenzoxazines, Imidazobenzoxazin-5-ones and Imidazobenzoxazin-5-thiones as Sodium Channel Blockers. Letters in Drug Design & Discovery, 2014, 11, 90-97.
- Shipping Conditions: Blue Ice
- Clinical Information: No Development Reported