(4-NH2)-Exatecan
CAT:
804-HY-145397-03
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
(4-NH2)-Exatecan
- CAS Number: 2495742-21-5
- UNSPSC Description: (4-NH2)-Exatecan (compound A), a topoisomerase inhibitor, is a derivative of Exatecan. (4-NH2)-Exatecan can be used in the synthesis of antibody-drug conjugates (ADCs)[1].
- Target Antigen: ADC Cytotoxin; Topoisomerase
- Type: Reference compound
- Related Pathways: Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/4-nh2-exatecan.html
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C1N2C(C(C(C2)=C3C4=C5CCC3)=NC4=CC=C5N)=CC6=C1COC([C@]6(O)CC)=O
- Molecular Weight: 403.43
- References & Citations: [1]Howard PW, et, al. Compounds and conjugates thereof. US20200306243A1.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported