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Ganoderic acid Mk

CAT: 0804-HY-N11643Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N11643Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ganoderic acid Mk (GA-Mk) is a triterpenoid acid, that can be isolated from the mycelia of Ganoderma lucidum. Ganoderic acid Mk is efficiently anti-proliferative and can induce apoptosis of HeLa cells by mitochondria-mediated pathway. Ganoderic acid Mk can be used for cervical cancer research[1][2].
CAS Number
110024-14-1
Product Name Alternative
GA-Mk
UNSPSC
12352211
Target
Apoptosis; Caspase; MMP; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ganoderic-acid-mk.html
Solubility
10 mM in DMSO
Smiles
O=C(/C(C)=C/CC(C(C1CC([C@@]2(C)C3=CCC4[C@](C)(CCC(C4(C)C)OC(C)=O)C3=CC[C@]12C)O)C)OC(C)=O)O
Molecular Formula
C34H50O7
Molecular Weight
570.76
References & Citations
[1]Liu R M, et al. Anti-proliferation and induced mitochondria-mediated apoptosis of ganoderic acid Mk from Ganoderma lucidum mycelia in cervical cancer HeLa cells[J]. Latin American Journal of Pharmacy, 2012, 31 (1) :43-50.|[2]Ding N, et al. Separation and determination of four ganoderic acids from dried fermentation mycelia powder of Ganoderma lucidum by capillary zone electrophoresis. J Pharm Biomed Anal. 2010 Dec 15;53 (5) :1224-30.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Caspase 3; Caspase 9

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