Ganoderic acid Mk

Ganoderic acid Mk

• CAS Number: 110024-14-1
• UNSPSC Description: Ganoderic acid Mk (GA-Mk) is a triterpenoid acid, that can be isolated from the mycelia of Ganoderma lucidum. Ganoderic acid Mk is efficiently anti-proliferative and can induce apoptosis of HeLa cells by mitochondria-mediated pathway. Ganoderic acid Mk can be used for cervical cancer research[1][2].
• Target Antigen: Apoptosis; Caspase; MMP; Reactive Oxygen Species
• Type: Natural Products
• Related Pathways: Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/ganoderic-acid-mk.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(/C(C)=C/CC(C(C1CC([C@@]2(C)C3=CCC4[C@](C)(CCC(C4(C)C)OC(C)=O)C3=CC[C@]12C)O)C)OC(C)=O)O
• Molecular Weight: 570.76
• References & Citations: [1]Liu R M, et al. Anti-proliferation and induced mitochondria-mediated apoptosis of ganoderic acid Mk from Ganoderma lucidum mycelia in cervical cancer HeLa cells[J]. Latin American Journal of Pharmacy, 2012, 31(1):43-50.|[2]Ding N, et al. Separation and determination of four ganoderic acids from dried fermentation mycelia powder of Ganoderma lucidum by capillary zone electrophoresis. J Pharm Biomed Anal. 2010 Dec 15;53(5):1224-30.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported