β-Glucocerebrosidase modulator 1

• UNSPSC Description:

  β-Glucocerebrosidase modulator 1 (Compound 28) is an allosteric modulator for β-Glucocerebrosidase with an EC50 of 9.0 μM and a Kd of 0.050 μM[1].

• Target Antigen:

  Glycosidase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/β-glucocerebrosidase-modulator-1.html

• Smiles:

  CN(C[C@@H](C1=CC(C(C)=C)=CC=C1)N)S(C2=CC(F)=CC(F)=C2)(=O)=O

• Molecular Weight:

  366.43

• References & Citations:

  [1]Palmer N, et al., Fragment-Based Discovery of a Series of Allosteric-Binding Site Modulators of β-Glucocerebrosidase. J Med Chem. 2024 Jul 11;67(13):11168-11181.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported