PI3K/Akt/mTOR-IN-2
CAT:
804-HY-146751-03
Size:
100 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

PI3K/Akt/mTOR-IN-2
- CAS Number: 2757804-89-8
- UNSPSC Description: PI3K/Akt/mTOR-IN-2 is a PI3K/AKT/mTOR pathway inhibitor. PI3K/Akt/mTOR-IN-2 possess anti-cancer effects and selectivity against MDA-MB-231 cells with IC50 value of 2.29 μM. PI3K/Akt/mTOR-IN-2 can induce cancer cell cycle arrest and apoptosis[1].
- Target Antigen: Akt; Apoptosis; mTOR; PI3K
- Type: Reference compound
- Related Pathways: Apoptosis;PI3K/Akt/mTOR
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/pi3k-akt-mtor-in-2.html
- Solubility: DMSO : ≥ 100 mg/mL
- Smiles: FC1=CC(F)=CC(C2OCCC3=C2NC4=C3C=CC=C4)=C1
- Molecular Weight: 285.29
- References & Citations: [1]Qin J, Sun X, Ma Y, et al. Design, synthesis and biological evaluation of novel 1,3,4,9-tetrahydropyrano[3,4-b]indoles as potential treatment of triple negative breast cancer by suppressing PI3K/AKT/mTOR pathway [published online ahead of print, 2021 Dec 31]. Bioorg Med Chem. 2021;55:116594.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported