Ganoderic acid TR

• Description:

  Ganoderic acid TR is a broad-spectrum inhibitor of influenza neuraminidase enzymes (NAs) . Ganoderic acid TR has IC50 values of 10.9 and 4.6 μM for H5N1 and H1N1 NAs, respectively. Ganoderic acid TR is limited by cytotoxicity and shows only weak activity against Oseltamivir (HY-13317) -resistant H1N1 viruses and influenza B viruses[1].

• UNSPSC:

  12352211

• Target:

  Influenza Virus

• Type:

  Natural Products

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/ganoderic-acid-tr.html

• Purity:

  98.0

• Solubility:

  DMSO : 5.5 mg/mL (ultrasonic; warming)

• Smiles:

  CC1(C)C(CC[C@]2(C)C3=CC[C@]4(C)[C@@H]([C@H](C)CC/C=C(C)/C(O)=O)C[C@H](O)[C@](C)4C3=CC[C@@]12[H])=O

• Molecular Formula:

  C30H44O4

• Molecular Weight:

  468.67

• References & Citations:

  [1]Zhu Q, et al. Inhibition of neuraminidase by Ganoderma triterpenoids and implications for neuraminidase inhibitor design. Sci Rep. 2015 Aug 26;5:13194.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  [862893-75-2]