EGFR Extracellular Domain (human, recombinant)

• Description:

  EGFR Extracellular Domain (human, recombinant)_x000D_ Catalog number: B2017257_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 100 µg_x000D_ Molecular Weight or Concentration: 95 kDa_x000D_ Supplied as: Solution_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: ˆ’80°C_x000D_ Keywords: Epidermal Growth Factor Receptor, ErbB-1, HER1_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Xiao Q, Li X, Li Y, Wu Z, Xu C, Chen Z, He W. Biological drug and drug delivery-mediated immunotherapy Acta Pharm Sin B. 2021 Apr;11(4):941-960._x000D_ 2: Banik SM, Pedram K, Wisnovsky S, Ahn G, Riley NM, Bertozzi CR. Lysosome-targeting chimaeras for degradation of extracellular proteins Nature. 2020 Aug;584(7820):291-297._x000D_ 3: Trajkovic K, Hsu C, Chiantia S, Rajendran L, Wenzel D, Wieland F, Schwille P, Brügger B, Simons M. Ceramide triggers budding of exosome vesicles into multivesicular endosomes Science. 2008 Feb 29;319(5867):1244-7._x000D_ 4: Li S, Schmitz KR, Jeffrey PD, Wiltzius JJ, Kussie P, Ferguson KM. Structural basis for inhibition of the epidermal growth factor receptor by cetuximab Cancer Cell. 2005 Apr;7(4):301-11._x000D_ 5: Leung K. (64)Cu-Bis(carboxymethyl)-1,4,8,11-tetraazabicyclo[6.6.2]hexadecane-(Gly-Ser-Gly)-Lys-Cys-Cys-Tyr-Ser-Leu 2012 Apr 26 [updated 2012 Jul 5]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004€“2013._x000D_ 6: Zhou S, Zhang W, Cai G, Ding Y, Wei C, Li S, Yang Y, Qin J, Liu D, Zhang H, Shao X, Wang J, Wang H, Yang W, Wang H, Chen S, Hu P, Sun L. Myofiber necroptosis promotes muscle stem cell proliferation via releasing Tenascin-C during regeneration Cell Res. 2020 Dec;30(12):1063-1077._x000D_ 7: Brindha S, Kibria MG, Saotome T, Unzai S, Kuroda Y. EGFR extracellular domain III expressed in Escherichia coli with SEP tag shows improved biophysical and functional properties and generate anti-sera inhibiting cancer cell growth Biochem Biophys Res Commun. 2021 May 28;555:121-127._x000D_ 8: Leung K. [O-(11)C-methyl]4-N-(3-Bromoanilino)-6,7-dimethoxyquinazoline 2009 May 6 [updated 2009 Jul 7]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004€“2013._x000D_ 9: Leung K. (64)Cu-1,4,7-Triazacyclononane-1,4-diacetic acid-(Gly-Ser-Gly)-Lys-Cys-Cys-Tyr-Ser-Leu 2012 Apr 26 [updated 2012 Jul 5]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004€“2013._x000D_ 10: Leung K. (64)Cu-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-panitumumab 2010 Jun 25 [updated 2010 Sep 30]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004€“2013._x000D_ _x000D_ Products Related to EGFR Extracellular Domain (human, recombinant) can be found at Proteins

• Short Description:

  Catalog Number: B2017257 (100 µg)_x000D_ The EGFR (Epidermal Growth Factor Receptor) Extracellular Domain (human, recombinant) is a recombinant version of the extracellular portion of the human EGFR protein. EGFR is a transmembrane glycoprotein that belongs to the receptor tyrosine kinase family and is involved in the regulation of cell growth, survival, proliferation, and differentiation. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3