BH3-Only Protein Detection Set

• Background:

  For images please see PDF data sheet

• Reactivity:

  Human

• Immunogen:

  Rabbit polyclonal antibodies were raised against peptides corresponding to amino acid sequences from each of the corresponding proteins.

• Clonality:

  Polyclonal

• Type:

  Detection Sets

• Purification:

  Antibodies are supplied as affinity chromatography purified IgG.

• Concentration:

  Antibody 1 mg/mL

• Buffer:

  PBS containing 0.02% sodium azide.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Stable at 4˚ C for three months, store at -20˚ C for up to one year.

• Background Reference 01:

  Lockshin RA, Osborne B, and Zakeri Z. Cell death in the third millennium. Cell Death Differ. 2000; 7:2-7.

• Background Reference 02:

  Cory S, Huang DCS, and Adams JM. The Bcl-2 family: roles in cell survival and oncogenesis. Oncogene 2003; 22:8590-607.

• Background Reference 03:

  Strasser A. The role of BH3-only proteins in the immune systems. Nat. Rev. 2005

• Background Reference 04:

  Inohara N, Ding L, Chen S, et al. harakiri, a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-XL. EMBO J. 1997; 16:1686-94.

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid