Products for Research Use Only
RegisterLogin

AL-4114

CAT: 0804-HY-116600Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-116600Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
AL-4114 is an aldose reductase inhibitor which can be utilized in research related to the prevention of diabetic cataractogenesis[1].
CAS Number
139911-05-0
UNSPSC
12352005
Target
Aldose Reductase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/al-4114.html
Smiles
O=C1NC(C2(C3=C(C4=C2C=C(F)C=C4OC)C(OC)=CC(F)=C3)N1)=O
Molecular Formula
C17H12F2N2O4
Molecular Weight
346.28
References & Citations
[1]Sastry SG, et al. Minimal effects of two aldose reductase inhibitors, AL-1576 and AL-4114, after subacute topical-ocular dosing on xenobiotic biotransformation in rabbits. Drug Metab Dispos. 1995 Oct;23 (10) :1094-8.|[2]Sastry SG, et al. Minimal effects of two aldose reductase inhibitors, AL-1576 and AL-4114, after subacute topical-ocular dosing on xenobiotic biotransformation in rabbits. Drug Metab Dispos. 1995 Oct;23 (10) :1094-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

AL 4114

structure given in first source

CAS Number139911-05-0
PubChem CID164424
IUPAC Name2,7-difluoro-4,5-dimethoxyspiro[fluorene-9,5'-imidazolidine]-2',4'-dione
Molecular FormulaC17H12F2N2O4
Molecular Weight346.28
XLogP2
Topological Polar Surface Area76.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count2
Heavy Atom Count25
Formal Charge0
Complexity557
SMILES
COC1=CC(=CC2=C1C3=C(C24C(=O)NC(=O)N4)C=C(C=C3OC)F)F
InChI
InChI=1S/C17H12F2N2O4/c1-24-11-5-7(18)3-9-13(11)14-10(4-8(19)6-12(14)25-2)17(9)15(22)20-16(23)21-17/h3-6H,1-2H3,(H2,20,21,22,23)
InChIKey
OVRBKKLFIRJPKY-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of AL 4114
CAS: 139911-05-0
CID: 164424
Formula: C17H12F2N2O4
MW: 346.28
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight346.28
XLogP32
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count2
Exact Mass346.07651319
Monoisotopic Mass346.07651319
Topological Polar Surface Area76.7 Ų
Heavy Atom Count25
Formal Charge0
Complexity557
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-118523AL-321
HY-W743888AL-LAD
HY-114154AL-438
HY-125641-01AL-34662
HY-125150AL-3138
HY-15709-01AL 082D06
HY-167011Al-28
HY-146009AL-470
HY-108645-01AL 8697
HY-117368AL-8417

Alternative Products

CatalogName
T25019-01AL 4114
TL311606VMAGEB3 Human shRNA Lentiviral Particle (Locus ID 4114)
SR302789MAGEB3 Human siRNA Oligo Duplex (Locus ID 4114)
TL311606MAGEB3 Human shRNA Plasmid Kit (Locus ID 4114)
B7784-50AL 8697
B4575-5AL 8810
C5271-50AL 34662
531435AL-8810
T69357-01AL-34662
T29814-01AL-3152

Popular Products