AL 082D06

• Description:

  AL 082D06 is a selective, nonsteroidal glucocorticoid receptor (GR) antagonist with Ki of 210 nM.

• Product Name Alternative:

  D06; D-06

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Glucocorticoid Receptor

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation; Vitamin D Related/Nuclear Receptor

• Field of Research:

  Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/AL-082D06.html

• Purity:

  98.92

• Solubility:

  DMSO : 7.5 mg/mL (ultrasonic; warming)

• Smiles:

  O=[N+] (C1=CC=C (Cl) C (C (C2=CC=C (N (C) C) C=C2) C3=CC=C (N (C) C) C=C3) =C1) [O-]

• Molecular Formula:

  C23H24ClN3O2

• Molecular Weight:

  409.91

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Miner JN, et al. A nonsteroidal glucocorticoid receptor antagonist. Mol Endocrinol. 2003 Jan;17 (1) :117-27.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  256925-03-8