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UROD Recombinant Protein

CAT: 0223-91-253Size: 0.05 mgDry Ice: YesHazardous: No
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CAT#:0223-91-253Size:0.05 mg
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Background
Uroporphyrinogen decarboxylase (UROD), is an enzyme of the heme biosynthetic pathway which belongs to the uroporphyrinogen decarboxylase family. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. UROD is a homodimeric enzyme that catalyzes the fifth step in heme biosynthesis: the elimination of carboxyl groups from the four acetate side chains of uroporphyrinogen III to yield coproporphyrinogen III. Defects in UROD are the cause of familial porphyria cutanea tarda (FPCT) and hepatoerythropoietic porphyria (HEP) .
CAS Number
9000-83-3
NCBI Gene ID
7389
Swiss Prot
P06132
Accession Number
P06132
Tag
N-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cancer, Obesity, Signal Transduction
Buffer
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 100mM NaCl, 1mM DTT, 1mM EDTA, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Calculated Molecular Weight
43 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Uroporphyrinogen decarboxylase
NCBI Organism
Homo sapiens
Other Product Names
Uroporphyrinogen Decarboxylase, UPD, URO-D, UROD
Species
Human
Physical Properties
Liquid

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