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UROD Antibody

CAT: 0223-29-631Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-29-631Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
UROD is the fifth enzyme of the heme biosynthetic pathway. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria.This gene encodes the fifth enzyme of the heme biosynthetic pathway. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria.
NCBI Gene ID
7389
Swiss Prot
P06132
Accession Number
NP_000365
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human UROD.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store UROD antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
40 kDa
Applications Notes
UROD antibody can be used for detection of UROD by ELISA at 1:62500. UROD antibody can be used for detection of UROD by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
UROD
NCBI Official Name
Uroporphyrinogen decarboxylase
NCBI Organism
Homo sapiens
Background Reference 01
Harraway, J.R., Ann. Clin. Biochem. 43 (PT 1), 80-82 (2006) .
Other Product Names
UROD, PCT, UPD
Tested Applications
ELISA, WB, IHC
Protein ID
71051616
Physical Properties
Liquid

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