Uroplakin-2 Recombinant Protein

• Background:

  Uroplakin-2 is a single-pass type I membrane protein that belongs to the uroplakin-2 family. Uroplakin-2 is a component of the asymmetric unit membrane (AUM) and expressed in the ureter, a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. Uroplakin-2 forms heterodimer with UPK1A that is necessary for exiting out of the endoplasmic reticulum (ER) . Uroplakin-2 may play an important role in regulating the assembly of the AUM. AUM is believed to strengthen the urothelium by preventing cell rupture during bladder distention.

• NCBI Gene ID:

  7379

• Swiss Prot:

  O00526

• Accession Number:

  O00526

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  14.84 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Uroplakin 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Uroplakin-2, UP2, Uroplakin II, UPII, UPK2

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3