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TIMP-2 Recombinant Protein

CAT: 0223-40-142-01Size: 0.002 mgDry Ice: NoHazardous: No
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CAT#:0223-40-142-01Size:0.002 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TIMP-2 is an extracellular inhibitor of MMPs including MMP1, 2, 3, 7, 8, 9, 10, 12, 13, 14, 15, 16 and 19. It belongs to the I35 (TIMP) family of irreversible protease inhibitors that function as key modulators of extracellular matrix degradation during tissue development and remodeling. TIMP-2 can also act through an MMP-independent mechanism inhibiting endothelial cell proliferation in vitro and demonstrates anti-angiogenic activities in vivo. Recombinant human TIMP-2 is a 21.8 kDa protein containing 194 amino acid residues.
NCBI Gene ID
7077
Swiss Prot
P16035
Accession Number
NP_003246.1
Type
Recombinant Proteins
Source
E. coli
Field of Research
Signal Transduction, Other
Shipping Conditions
Room Temp
Storage Conditions
The lyophilized TIMP-2 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted TIMP-2 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing TIMP-2 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
NCBI Official Name
TIMP metallopeptidase inhibitor 2
NCBI Organism
Homo sapiens
Other Product Names
DDC8, CSC-21K, Metalloproteinase inhibitor 2, TIMP-2
Species
Human
Protein ID
4507511
Physical Properties
Lyophilized

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