Relaxin-2 Recombinant Protein

• Background:

  Relaxin-2 is a peptide hormone structurally related to insulin, which is expressed in the placenta, decidua, prostate, and in the ovary during pregnancy. Of the three known relaxin genes, Relaxin-2 is the only relaxin known to circulate in the blood. Relaxin-2 binds specifically to the LGR7 and LGR8 receptors, previously identified as an "orphan” G protein coupled receptors. Signaling by Relaxin-2 through its target receptors enhances the growth of pubic ligaments and ripening of the cervix during birth. Recombinant Relaxin-2 is a nonglycosylated 6.0 kDa disulfide linked heterodimeric protein consisting of a 24 amino acid A-chain and a 29 amino acid B-chain.

• NCBI Gene ID:

  6019

• Swiss Prot:

  P04090

• Accession Number:

  NP_005050.2

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Neuroscience, Signal Transduction

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  The lyophilized Relaxin-2 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted Relaxin-2 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing Relaxin-2 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

• NCBI Official Name:

  Relaxin 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  H2, RLXH2, H2-RLX, bA12D24.1.1, bA12D24.1.2, Prorelaxin H2

• Species:

  Human

• Protein ID:

  20143935

• Physical Properties:

  Lyophilized