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TRIM5 Recombinant Protein

CAT: 0223-92-254Size: 0.05 mgDry Ice: YesHazardous: No
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CAT#:0223-92-254Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Tripartite motif-containing Motif 5 is a protein that in humans is encoded by the TRIM5 gene.It is a 493 amino acids protein that belongs to the TRIM/RBCC family.It contains 1 B box-type zinc finger, 1 B30.2/SPRY domain and 1 RING-type zinc finger. TRIM5 present in the cytoplasm recognizes motifs within the capsid proteins and interferes with the uncoating process, therefore preventing successful reverse transcription and transport to the nucleus of the viral genome. The exact mechanism of action has not been shown conclusively, but capsid protein from restricted viruses is removed by proteasome-dependent degradation
CAS Number
9000-83-3
NCBI Gene ID
85363
Swiss Prot
Q9C035
Accession Number
Q9C035
Tag
N-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cancer, Infectious Disease, Signal Transduction
Buffer
Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Calculated Molecular Weight
30.8 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Tripartite motif containing 5
NCBI Organism
Homo sapiens
Other Product Names
Tripartite motif-containing protein 5, RING finger protein 88, TRIM5, RNF88, RNF88
Species
Human
Physical Properties
Liquid

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