TRIM5 Recombinant Protein

• Background:

  Tripartite motif-containing Motif 5 is a protein that in humans is encoded by the TRIM5 gene.It is a 493 amino acids protein that belongs to the TRIM/RBCC family.It contains 1 B box-type zinc finger, 1 B30.2/SPRY domain and 1 RING-type zinc finger. TRIM5 present in the cytoplasm recognizes motifs within the capsid proteins and interferes with the uncoating process, therefore preventing successful reverse transcription and transport to the nucleus of the viral genome. The exact mechanism of action has not been shown conclusively, but capsid protein from restricted viruses is removed by proteasome-dependent degradation

• NCBI Gene ID:

  85363

• Swiss Prot:

  Q9C035

• Accession Number:

  Q9C035

• Tag:

  N-6 His tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Cancer, Infectious Disease, Signal Transduction

• Buffer:

  Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

• Shipping Conditions:

  Dry Ice

• Calculated Molecular Weight:

  30.8 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Tripartite motif containing 5

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Tripartite motif-containing protein 5, RING finger protein 88, TRIM5, RNF88, RNF88

• Species:

  Human

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3