Products for Research Use Only

TIMP-1 Recombinant Protein

CAT: 0223-91-412Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-91-412Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13, and MMP-16. TIMP-1 does not act on MMP-14.
CAS Number
9000-83-3
NCBI Gene ID
7076
Swiss Prot
P01033
Accession Number
P01033
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Cancer, Cell Cycle, Signal Transduction
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
21.75 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
TIMP metallopeptidase inhibitor 1
NCBI Organism
Homo sapiens
Other Product Names
Metalloproteinase Inhibitor 1, Erythroid-Potentiating Activity, EPA, Fibroblast collagenase Inhibitor, Collagenase Inhibitor, Tissue Inhibitor of Metalloproteinases 1, TIMP-1, TIMP1, CLGI, TIMP
Species
Human
Physical Properties
Lyophilized