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Tim-1 Recombinant Protein

CAT: 0223-90-546Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0223-90-546Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to viral infections. The unique structure of TIM immunoglobulin variable region domains allows highly specific recognition of phosphatidylserine (PtdSer), exposed on the surface of apoptotic cells. TIM-1 (T cell-immunoglobulinmucin; also KIM-1 and HAVcr-1) is a 100 kDa, type I transmembrane glycoprotein member of the TIM family of immunoglobulin superfamily molecules. There are two cytoplasmic alternate splice forms of TIM1. One is a long (359 aa) kidney form termed TIM-1b, and one is a short (334 aa) liver form termed TIM-1a. TIM-1, important for asthma and allergy, is preferentially expressed on T-helper 2 (Th2) cells and functions as a potent costimulatory molecule for T cell activation.
CAS Number
9000-83-3
NCBI Gene ID
26762
Swiss Prot
P23785
Accession Number
NP_036338
Tag
Fc Tag
Type
Recombinant Proteins
Source
CHO cells
Field of Research
Apoptosis, Growth Factors, Homeostasis, Immunology, Neuroscience, Signal Transduction
Buffer
Lyophilized from 0.2um-filtered solution in PBS. Reconstitute with 100 μ l sterile water. Add 1X PBS to the desired protein concentration.
Shipping Conditions
Room Temp
Storage Conditions
Stable for at least 1 year after receipt when stored at -20˚ C. Working aliquots are stable for up to 3 months when stored at -20˚ C.
Applications Notes
This recombinant proteins is for research use only.
NCBI Official Name
Hepatitis A virus cellular receptor 1
NCBI Organism
Homo sapiens
Other Product Names
TIM1, KIM1, TIMD1, Hepatitis A Virus Cellular Receptor 1, T Cell Immunoglobulin and Mucin Domain-containing Protein 1, T Cell Membrane Protein 1
Species
Human
Protein ID
153085427
Physical Properties
Lyophilized

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