ST6GAL1 Recombinant Protein

• Background:

  The ST6GAL1 gene encodes beta -Galactosamide alpha-2,6-Sialyltransferase 1. It is a type II membrane protein and is localized to the trans-Golgi network. It catalyzes 2,6-sialylation of Gal beta 1,4-GlcNAc structures on N-glycans. ST6GAL1 is highly expressed in the liver and other tissues. ST6GAL1 deficiency causes abnormalities in B-cell immunoreactivity. The expression and activity of ST6GAL1 are associated with tumor metastasis in breast and colon cancers. The majority of ST6GAL1 in the liver is cleaved and secreted into the serum and may be used as a biomarker for hepatitis diseases.

• NCBI Gene ID:

  6480

• Swiss Prot:

  P15907

• Accession Number:

  P15907

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Immunology, Signal Transduction, Other

• Buffer:

  Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

• Shipping Conditions:

  Dry Ice

• Calculated Molecular Weight:

  44.6 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  ST6 beta-galactosamide alpha-2,6-sialyltranferase 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Beta-Galactoside Alpha-2, 6-Sialyltransferase 1, Alpha 2, 6-ST 1, B-Cell Antigen CD75, CMP-N-Acetylneuraminate-Beta-Galactosamide-Alpha-2, ST6Gal I, ST6GalI, Sialyltransferase 1, ST6GAL1, SIAT1

• Species:

  Human

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3