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ST6GAL1 Recombinant Protein

CAT: 0223-91-452Size: 0.05 mgDry Ice: YesHazardous: No
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CAT#:0223-91-452Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The ST6GAL1 gene encodes beta -Galactosamide alpha-2,6-Sialyltransferase 1. It is a type II membrane protein and is localized to the trans-Golgi network. It catalyzes 2,6-sialylation of Gal beta 1,4-GlcNAc structures on N-glycans. ST6GAL1 is highly expressed in the liver and other tissues. ST6GAL1 deficiency causes abnormalities in B-cell immunoreactivity. The expression and activity of ST6GAL1 are associated with tumor metastasis in breast and colon cancers. The majority of ST6GAL1 in the liver is cleaved and secreted into the serum and may be used as a biomarker for hepatitis diseases.
CAS Number
9000-83-3
NCBI Gene ID
6480
Swiss Prot
P15907
Accession Number
P15907
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Immunology, Signal Transduction, Other
Buffer
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Calculated Molecular Weight
44.6 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
NCBI Organism
Homo sapiens
Other Product Names
Beta-Galactoside Alpha-2, 6-Sialyltransferase 1, Alpha 2, 6-ST 1, B-Cell Antigen CD75, CMP-N-Acetylneuraminate-Beta-Galactosamide-Alpha-2, ST6Gal I, ST6GalI, Sialyltransferase 1, ST6GAL1, SIAT1
Species
Human
Physical Properties
Liquid

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