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ST6GAL1 Antibody

CAT: 0223-60-768Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-768Size:400 µL
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Background
This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Three transcript variants encoding two different isoforms have been described.
NCBI Gene ID
6480
Swiss Prot
P15907
Accession Number
P15907
Host
Rabbit
Reactivity
Human
Immunogen
This ST6GAL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-206 amino acids from the Central region of human ST6GAL1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
47 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ST6GAL1
NCBI Official Name
Beta-galactoside alpha-2,6-sialyltransferase 1
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Mondal, S., et al. Leuk. Res. 34 (4) :463-470 (2010)
Background Reference 03
Lee, M., et al. Oncol. Rep. 23 (3) :757-761 (2010)
Background Reference 04
Daly, A.K., et al. Nat. Genet. 41 (7) :816-819 (2009)
Other Product Names
Beta-galactoside alpha-2,6-sialyltransferase 1, Alpha 2,6-ST 1, B-cell antigen CD75, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1, ST6Gal I, ST6GalI, Sialyltransferase 1, ST6GAL1, SIAT1
Tested Applications
WB
Protein ID
115445
Physical Properties
Liquid

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