NTB-A / SLAMF6 Recombinant Protein

• Background:

  The SLAM family of receptors is composed of six members named SLAM (CD150) ; 2B4 (CD244) ; Ly-9 (CD229) ; CD84; natural killer, T and B cell antigen (NTB-A; Ly108 in the mouse. Most, if not all, immune cell types express more than one SLAM family receptor. All six SLAM-related genes are located within a 400–500 kilobase (kb) genomic segment on chromosome 1 in humans and mice. This feature implies that the genes that encode the SLAM family were created by serial gene duplication.

• NCBI Gene ID:

  114836

• Swiss Prot:

  Q96DU3

• Accession Number:

  NP_001171643.1

• Tag:

  His Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Purity:

  >95% as determined by SDS-PAGE.

• Buffer:

  PBS, pH7.4

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  25.0 kDa

• Applications Notes:

  This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 25.0 kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

• NCBI Official Name:

  SLAM family member 6

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Veillette A., et al. 2007, Immunity., 27 (5), 698-710.

• Background Reference 02:

  Detre C., et al. 2010, Semin Immunopathol., 32 (2), 157-71.

• Background Reference 03:

  Nakajima H., et al. 2010, Semin Immunopathol., 32 (2), 157-71.

• Other Product Names:

  NTB-A, SLAMF6, Ly108, NK-T-B-antigen, CD352, KALI

• Tested Applications:

  WB

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3