SLAMF6 Antibody

CAT: 0223-30-592Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-30-592Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SLAMF6 is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs) . It may function as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs) . It may function as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
NCBI Gene ID
114836
Swiss Prot
B2R8X8
Accession Number
NP_443163
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SLAMF6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1309 - Human Placenta Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SLAMF6 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
34 kDa
Applications Notes
SLAMF6 antibody can be used for detection of SLAMF6 by ELISA at 1:62500. SLAMF6 antibody can be used for detection of SLAMF6 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
SLAMF6
NCBI Official Name
SLAM family member 6
NCBI Organism
Homo sapiens
Background Reference 01
Claus, M., (er) Front. Biosci. 13, 956-965 (2008) .
Other Product Names
SLAMF6, KALI, KALIb, Ly108, MGC104953, NTB-A, NTBA, SF2000, CD352
Tested Applications
ELISA, WB
Protein ID
16418407
Physical Properties
Liquid

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