Cathepsin D Recombinant Protein

• Background:

  The protein acid protease active in intracellular protein breakdown and involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. It is specificity similar to, but narrower than, that of pepsin A and it does not cleave the 4-Gln-|-His-5 bond in B chain of insulin. It consists of a light chain and a heavy chain and expressed in the aorta extrcellular space. The Val-58 allele is significantly overrepresented in demented patients (11.8%) compared with non-demented controls (4.9%) . Carriers of the Val-58 allele have a 3.1-fold increased risk for developing AD than non-carriers.It belongs to the peptidase A1 family

• NCBI Gene ID:

  1509

• Swiss Prot:

  P07339

• Accession Number:

  P07339

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Cancer, Cell Cycle, Neuroscience, Signal Transduction, Other

• Buffer:

  Supplied as a 0.2 um filtered solution of 20mM MES, 150mM NaCl, pH 5.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

• Shipping Conditions:

  Dry Ice

• Calculated Molecular Weight:

  43.8 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Cathepsin D

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Cathepsin D, CTSD, CPSD

• Species:

  Human

• Protein ID:

  701165624

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3