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Cathepsin B Recombinant Protein

CAT: 0223-91-365Size: 0.05 mgDry Ice: YesHazardous: No
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CAT#:0223-91-365Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cathepsin B is an enzymatic protein belonging to the peptidase (or protease) families. The protein encoded by this gene is a lysosomal cysteine protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is a member of the peptidase C1 family. At least five transcript variants encoding the same protein have been found for this gene. Cystatin-B / CSTB is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B. Cystatin-B / CSTB is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Cystatin-B / CSTB is also thought to play a role in protecting against the proteases leaking from lysosomes
CAS Number
9000-83-3
NCBI Gene ID
1508
Swiss Prot
P07858
Accession Number
P07858
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Cancer, Neuroscience, Signal Transduction
Buffer
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Calculated Molecular Weight
36.9 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Cathepsin B
NCBI Organism
Homo sapiens
Other Product Names
Cathepsin B, APP Secretase, APPS, Cathepsin B1, CTSB, CPSB
Species
Human
Protein ID
767983919
Physical Properties
Liquid

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