Cathepsin L Recombinant Protein

• Background:

  Mouse Cathepsin L is a lysosomal cysteine proteinase which is a member of the peptidase C1 family. This protein is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Cathepsin L plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. Cathepsin L has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria.

• NCBI Gene ID:

  13039

• Swiss Prot:

  P06797

• Accession Number:

  P06797

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Cell Cycle, Neuroscience, Signal Transduction

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  36.8 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Cathepsin L

• NCBI Organism:

  Mus musculus

• Other Product Names:

  Cathepsin L1, Major excreted protein, p39 cysteine proteinase, Ctsl1, CTSL

• Species:

  Mouse

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3