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GALE Recombinant Protein

CAT: 0223-91-243Size: 0.05 mgDry Ice: YesHazardous: No
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CAT#:0223-91-243Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The enzyme UDP-Glucose 4-Epimerase (GALE) is a homodimeric epimerase found in bacterial, plant and mammalian cells. UDP-Glucose 4-Epimerase performs the final step in the Leloir pathway of Galactose metabolism, it catalyzes two distinct but analogous reactions: the epimerization of UDP-Gglucose to UDP-Galactose and the epimerization of UDP-N-Acetylglucosamine to UDP-N-Acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids.
CAS Number
9000-83-3
NCBI Gene ID
2582
Swiss Prot
Q14376
Accession Number
Q14376
Tag
N-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cancer, Obesity, Signal Transduction
Buffer
Supplied as a 0.2 um filtered solution of 50mM TrisHCl, 150mM NaCl, 2mM DTT, 1mM EDTA, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Calculated Molecular Weight
40.44 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
UDP-galactose-4-epimerase
NCBI Organism
Homo sapiens
Other Product Names
UDP-Glucose 4-Epimerase, Galactowaldenase, UDP-Galactose 4-Epimerase, GALE
Species
Human
Physical Properties
Liquid

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