PSMC6 Recombinant Protein

• Background:

  The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 α subunits and 2 rings are composed of 7 β subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.

• NCBI Gene ID:

  5706

• Swiss Prot:

  P62333

• Accession Number:

  NP_002797

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Cell Cycle

• Purity:

  95%

• Buffer:

  3

• Shipping Conditions:

  Dry Ice

• Storage Conditions:

  Store in working aliquots at -70˚ C. Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

• Calculated Molecular Weight:

  44.7 kDa (Calculated)

• Applications Notes:

  This recombinant protein can be used for WB, ELISA, MS.

• NCBI Official Name:

  Proteasome (prosome, macropain) 26S subunit, ATPase, 6

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  P44, p42, SUG2, CADP44, HEL-S-73, 26S protease regulatory subunit 10B, 26S proteasome AAA-ATPase subunit RPT4

• Tested Applications:

  ELISA, WB, MS

• Species:

  Human

• Protein ID:

  24430160

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3