PSMC6 Recombinant Protein

CAT: 0223-XW-RP3212Size: 0.05 mgDry Ice: YesHazardous: No
CAT#:0223-XW-RP3212Size:0.05 mg
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Background
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 α subunits and 2 rings are composed of 7 β subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.
CAS Number
9000-83-3
NCBI Gene ID
5706
Swiss Prot
P62333
Accession Number
NP_002797
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cell Cycle
Purity
95%
Buffer
3
Shipping Conditions
Dry Ice
Storage Conditions
Store in working aliquots at -70˚ C. Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Calculated Molecular Weight
44.7 kDa (Calculated)
Applications Notes
This recombinant protein can be used for WB, ELISA, MS.
NCBI Official Name
Proteasome (prosome, macropain) 26S subunit, ATPase, 6
NCBI Organism
Homo sapiens
Other Product Names
P44, p42, SUG2, CADP44, HEL-S-73, 26S protease regulatory subunit 10B, 26S proteasome AAA-ATPase subunit RPT4
Tested Applications
ELISA, WB, MS
Species
Human
Protein ID
24430160
Physical Properties
Liquid

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