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TGF-a Recombinant Protein

CAT: 0223-40-573Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-40-573Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TGF-α is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-α induces transformation anchorage independence in cultured cells. Human, murine and rat TGF-α are cross-species reactive. Recombinant human TGF-α is a 50 amino acid polypeptide (5.5 kDa) which shares approximately 40% sequence homology with EGF, including 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds.
CAS Number
9000-83-3
NCBI Gene ID
7039
Swiss Prot
P01135
Accession Number
NP_001093161.1
Type
Recombinant Proteins
Source
E. coli
Field of Research
Growth Factors
Purity
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Shipping Conditions
Room Temp
Storage Conditions
The lyophilized TGF-a recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted TGF-a stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing TGF-a recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
NCBI Official Name
Transforming growth factor, alpha
NCBI Organism
Homo sapiens
Other Product Names
TFGA, Protransforming growth factor alpha, EGF-like TGF, TGF-alpha
Species
Human
Protein ID
153791414
Physical Properties
Lyophilized

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