TGF beta RII Recombinant Protein

• Background:

  Transforming growth factor- beta (TGF- beta) is an essential regulator in the processes of development, cell proliferation, and extracellular matrix deposition. TGF- beta regulates cellular processes by binding to three high-affinity cell surface receptors: TGF- beta receptor type I (TGF- beta -RI), TGF- beta receptor type II (TGF- beta -RII), and TGF- beta beta receptor type III (TGF- beta -RIII) . TGF- beta RII is consists of a C-terminal protein kinase domain and an N-terminal ectodomain and belongs to transforming growth factor-beta (TGF- beta) receptor subfamily. TGF- beta RII has a protein kinase domain which can form a heterodimeric complex with another receptor protein and bind TGF-beta. This receptor/ligand complex phosphorylates protein will enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation.

• NCBI Gene ID:

  21813

• Swiss Prot:

  Q62312-2

• Accession Number:

  Q62312-2

• Tag:

  C-Fc tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Signal Transduction

• Buffer:

  Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  42.3 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Transforming growth factor, beta receptor II

• NCBI Organism:

  Mus musculus

• Other Product Names:

  TGF-beta receptor type-2, TGFR-2, TGF-beta type II receptor, Transforming growth factor-beta receptor type II, TGF-beta receptor type II, TbetaR-II, Tgfbr2

• Species:

  Mouse

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3