TIM-3 Recombinant Protein

CAT: 0223-91-327Size: 0.05 mgDry Ice: NoHazardous: No
CAT#:0223-91-327Size:0.05 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
T-Cell Membrane Protein 3 (TIM3) is a single-pass type I membrane protein that belongs to the TIM family of immunoglobulin superfamily. TIM3 includes a signal sequence (aa 1-21), an extracellular region (aa 22-202) with one Ig-like V-type domain, a transmembrane segment (aa 203-223), and a cytoplasmic domain (aa 224 - 301) . TIM3 regulates macrophage activation, inhibits T-helper type 1 lymphocyte (Th1) -mediated auto- and alloimmune responses and promotes immunological tolerance. It may be also involved in T-cell homing and as a receptor for LGALS9.
CAS Number
9000-83-3
NCBI Gene ID
84868
Swiss Prot
Q8TDQ0
Accession Number
Q8TDQ0
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Cancer, Cell Cycle, Immunology
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
20.86 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Hepatitis A virus cellular receptor 2
NCBI Organism
Homo sapiens
Other Product Names
Hepatitis A Virus Cellular Receptor 2, HAVcr-2, T-Cell Immunoglobulin and Mucin Domain-Containing Protein 3, TIMD-3, T-Cell Membrane Protein 3, TIM-3, HAVCR2, TIM3, TIMD3
Species
Human
Protein ID
530384505
Physical Properties
Lyophilized

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