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Mouse TIM-3 Recombinant Protein

CAT: 0908-RP1470M-01Size: 5 µgDry Ice: NoHazardous: No
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CAT#:0908-RP1470M-01Size:5 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TIM-3 is a transmembrane protein of T lymphocytes (CD4+ and CD8+ T cells), myeloid cells (monocytes, macrophages, DC, mast cells, NK cells) or various cells in different tumor types. The receptor is an immune checkpoint and together with other inhibitory receptors including programmed cell death protein 1 (PD-1) and lymphocyte activation gene 3 protein (LAG3) mediate the CD8+ T-cell exhaustion in terms of proliferation and secretion of cytokines such as TNF-alpha, IFN-gamma and IL-2.
Description
The Mouse TIM-3 yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Mouse TIM-3 applications are for cell culture, ELISA standard, and Western Blot Control. Mouse TIM-3 yeast-derived recombinant protein can be purchased in multiple sizes. Mouse TIM-3 Specifications: (Molecular Weight: 19.3 kDa) (Amino Acid Sequence: RSLENAYVFE VGKNAYLPCS YTLSTPGALV PMCWGKGFCP WSQCTNELLR TDERNVTYQK SSRYQLKGDL NKGDVSLIIK NVTLDDHGTY CCRIQFPGLM NDKKLELKLD IKAAKVTPAQ TAHGDSTTAS PRTLTTERNG SETQTLVTLH NNNGTKISTW ADEIKDSGET IRTA (174) ) (Gene ID: 171285) . For research use only.
Applications
Cell Culture, ELISA Standard, ELISpot Control, Western Blot Control
Homology
Mus musculus (house mouse)
Purity
>98% as visualized by SDS-PAGE analysis.
Molecular Weight
19.3 kDa
Storage Temperature
-20°C

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