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Stathmin Recombinant Protein

CAT: 0223-91-154Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-91-154Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Stathmin (STMN1) is a ubiquitous cytosolic phosphoprotein which belongs to the Stathmin family. STMN1 is expressed in many tissues, with the highest expression in the brain, spinal cord, and cerebellum. It can also be expressed in the colon, ovary, placenta, uterus, and trachea. STMN1 participates in the regulation of the microtubule filament structure by destabilizing microtubules. STMN1 promotes the disassembly of microtubules and prevents assembly. STMN1 is involved in the control of the learned and innate fear. STMN1 is an intracellular relay integrating regulatory signals of the cellular environment and as an Oncoprotein in regulation of the cell cycle. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Mutation in STMN1 effects cell homeostasis that may lead to tumorigenicity.
CAS Number
9000-83-3
NCBI Gene ID
3925
Swiss Prot
P16949
Accession Number
P16949
Tag
C-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cancer, Homeostasis, Signal Transduction, Other
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
18.37 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Stathmin 1
NCBI Organism
Homo sapiens
Other Product Names
Stathmin, Leukemia-Associated Phosphoprotein p18, Metablastin, Oncoprotein 18, Op18, Phosphoprotein p19, pp19, Prosolin, Protein Pr22, pp17, STMN1, C1orf215, LAP18
Species
Human
Protein ID
530394832
Physical Properties
Lyophilized

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