Stathmin 1 (phospho Ser25) Antibody

• Background:

  Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear

• NCBI Gene ID:

  3925

• Swiss Prot:

  P16949

• Accession Number:

  NP_001138926.1

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Stathmin 1 (Phospho-Ser25) antibody was raised against a peptide sequence around phosphorylation site of serine 25 (I-L-S (p) -P-R) derived from Human Stathmin 1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Phospho-Specific

• Purification:

  Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

• Concentration:

  1 mg/mL

• Buffer:

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  Phospho-Specific

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight:

  19 kDa

• Specificity:

  This antibody detects endogenous level of Stathmin 1 only when phosphorylated at serine 25.

• Applications Notes:

  Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

• Symbol:

  STMN1

• NCBI Official Name:

  Stathmin 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Boehm M, et al. (2002) EMBO J 21 (13) : 3390-3401. Vadlamudi RK, et al. (2005) Mol Cell Biol 25 (9) : 3726-3736. Zilfou JT, et al. (2001) Mol Cell Biol 21 (12) : 3974-3985. Biernat J, et al. (2002) Mol Biol Cell 13 (11) : 4013-4028.

• Other Product Names:

  Lag, SMN, OP18, PP17, PP19, PR22, LAP18, C1orf215, BIM, STMN1, STN1, stathmin

• Tested Applications:

  WB, IHC

• Protein ID:

  224451142

• Physical Properties:

  Liquid