SIRPG Recombinant Protein

• Background:

  Signal-regulatory protein gamma (SIRPG or SIRP-gamma) is also known as CD172 antigen-like family member B (CD172g), Signal-regulatory protein beta-2 (SIRPB2), is a single-pass type I membrane protein. SIRPG is expressed on CD4+ T-cells, CD8+ T-cells, CD56-bright natural killer (NK) cells, CD20+ cells, and all activated NK cells. SIRPG interacts with CD47. On binding with CD47, CD172g mediates cell-cell adhesion.

• NCBI Gene ID:

  55423

• Swiss Prot:

  Q9P1W8

• Accession Number:

  AAH64532

• Tag:

  C-Fc Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Immunology

• Purity:

  >95% as determined by SDS-PAGE.

• Buffer:

  50 mM tris, 100 mM glycine, pH7.5

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  63.7 kDa

• Applications Notes:

  This recombinant protein can be used for WB. For research use only.

• NCBI Official Name:

  Signal-regulatory protein gamma

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ichigotani Y., et al., 2000, J. Hum. Genet. 45:378-382.

• Background Reference 02:

  Piccio L., et al., 2005, Blood 105:2421-2427.

• Other Product Names:

  SIRPG, CD172g, SIRPB2, SIRP-gamma, SIRP-b2, SIRP-beta-2, Cripto-1

• Tested Applications:

  WB

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3